CHIRAL CATALYSTS AND SCREENING
Chiral Quest provides 'kits' containing a broad array of catalysts for rapid evaluation on a research scale by our customer. After a particular catalyst is selected for scale-up, Chiral Quest supports the customer with supply of grams-to-kilo quantities for commercial manufacture. We have practical manufacturing processes for five catalysts.
Customers benefit from our expertise in developing the optimum process for introduction of a chiral center. When they provide proprietary targets, we screen catalysts and reaction conditions to define the optimal process.
This screening service can be as simple as identifying a catalyst that provides the target chiral purity, or as complex as a fully developed commercial process ready for technology transfer to manufacturing.
| Chiral Quest has developed and commercialized five asymmetric hydrogenation ligands and their respective catalysts: |
• C3-TunePhos
• DuanPhos
• TangPhos
• Binapine
• Binaphane |
Click here for additional technical information |
Chiral Quest provides a 'Catalyst Kit' for evaluation. These catalysts are air-stable, and can be weighed and handled without a glove-box.
The catalyst kit includes 200 mgs each of the following catalysts:
• [RuCl((R)-C3-TunePhos)(P-Cymene)]Cl
• Rh((1S,1S',2R,2R')-TangPhos)(COD)BF4
• Rh((S)-BINAPINE)(COD)BF4
• Rh((R)-BINAPHANE)(COD)BF4
• Rh((1R,1R',2S,2S')-DuanPhos)(COD)BF4 |
